Trust. Experience. Reliability. Quality.

Advancing Nanomedicines from Formulation to Scale-Up to Clinical Supply.

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Innovative. Collaborative. Accountable.

Enhancing the lives of patients and delivering trusted results.

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Commitment. Integrity. Courage.

Shaping the Future of Drug Delivery.

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Phosphorex, a CDMO with two decades of experience, offering particle-based drug delivery solutions.

Phosphorex, a CDMO with two decades of experience, offering particle-based drug delivery solutions.

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Our Capabilities

Lipid Nanoparticles for Nucleic Acid Delivery

Lipid Nanoparticles for Nucleic Acid Delivery

At Phosphorex, we offer a range of innovative solutions for the delivery of nucleic acids, facilitating cellular entry and endosome escape including liposomes, lipid nanoparticles, and cationic polymers.

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Polymeric Nanoparticles for Targeted Delivery

Polymeric Nanoparticles for Targeted Delivery

Our team accelerates the development of nanomedicines by fabricating nanoparticles, modifying their surface for different targeting needs, scaling up to support preclinical and IND-enabling studies and developing GMP processes.

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Polymeric Microspheres for Sustained Release Delivery

Polymeric Microspheres for Sustained Release Delivery

Our team of experts offer tailored solutions to optimize a drug's release and long-acting profile to achieve the desired therapeutic effect, reduce side effects and enhance patient compliance.

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Our Service Offerings

Formulation Feasibility & Optimization Formulation Feasibility & Optimization

Formulation Feasibility & Optimization

Process Development & Scale Up Process Development & Scale Up

Process Development & Scale Up

Pre-clinical Batch Manufacturing Pre-clinical Batch Manufacturing

Pre-clinical Batch Manufacturing

cGMP Manufacturing cGMP Manufacturing

cGMP Manufacturing

Analytical Services Analytical Services

Analytical Services

What's New at Phosphorex

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Case Study: Development of Nanoparticles for the Systemic Delivery of Antisense Oligonucleotides to the Central Nervous System

Phosphorex's director of nucleic delivery presents on Nanoparticles for the delivery of ASO to the CNS

A Case Study: Nanoparticle Formulation Enables Systemic Delivery of a Therapeutic Agent to Treat Glioblastoma

In collaboration with Brown University, Phosphorex presents on the use the nanoparticle formulation, to enable Systematic Delivery of Tx Agent to treat GBM

Phosphorex Expands Facilities

Phosphorex announced today the acquisition of new laboratory and office space in Hopkinton, MA to meet the increasing demand for its products and services.

Pharma Talk Radio Podcast, Future Outlook for Novel Drug Delivery

Partnership Opportunities in Drug Delivery (PODD) conference explores the value of drug delivery technologies both to patients and pharma with a focus on the future direction of the field.

Delivering Expert Services

Phosphorex leverages its expertise in particle-based formulations to address the challenges associated with therapeutic agent delivery. We understand the need for specific tissue or cell targeting to maximize therapeutic effects, especially in cases where current modalities lack such capabilities. Read more

Therapeutic Modalities

Therapeutic Modalities

We have worked with numerous advanced drug payload types designed to revolutionize delivery in various therapeutic areas. We support tailored solutions to address specific application needs in the following modalities

  • Ex-vivo Cell Therapy
  • In-vivo Cell Engineering
  • Gene Therapy
  • Gene Silencing
  • Vaccines
  • Immuno-oncology
  • Long-acting Injectables

Drug Payloads

Drug Payloads

Our experience spans a range of payloads suited to a variety of applications and research needs. Our team is committed to providing the highest quality standard of services to our clients with efficacy, stability, and safety as our top priority.

  • siRNA & ASO
  • mRNA
  • DNA
  • small molecules
  • Peptides
  • Protein
  • mAbs

We have been working with Phosphorex for about 3 years developing particulate delivery systems for both small molecule and gene based therapeutics to treat retinal degeneration. We are a small company, so in addition to the very challenging technical issues, there were resource constraints and aggressive timelines. Despite those challenges Phosphorex delivered for us...and in a very collegial way....awesome group of folks to work with.

Marty Emanuele, PhD CEO Visgenx, Inc
Drug Carriers

Drug Carriers

Our specialized team is dedicated to supporting innovative drug delivery solutions that enhance the efficacy and safety of a wide range of therapeutics. We are committed to advancing the field of drug delivery, ensuring optimal outcomes for patients and maximizing the potential of your therapies.

  • Lipid Nanoparticles
  • Liposomes
  • Polymeric Nanoparticles
  • Polymeric Microspheres
  • Micelles
  • Lipid-polymer Hybrid
  • Polyplexes

About Phosphorex

With 18 years of experience for particle-based formulation and development, we are committed to ensuring our client's success every step of the way, from proof of concept to clinical studies. We are excited to offer cGMP capabilities in 2024.


Our Mission

Phosphorex is a CDMO specializing in innovative and proven particle-based drug delivery solutions. Our two-decade of experience, fortified with skilled and dedicated employees (scientists), yields trusted and collaborative Pharma & Biotech partnerships.

Our Leadership

Our leadership team is comprised of experienced and dedicated individuals who are committed to ensuring the success of our organization.

Careers at Phosphorex

We are excited that you're considering joining our team. Our employees are our greatest assets, and we are committed to offering a supportive and collaborative work environment.

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